Please use this identifier to cite or link to this item:
http://localhost:8080/xmlui/handle/123456789/3418Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Beesu, Mallesh | - |
| dc.contributor.author | Kokatla, Hari Prasad | - |
| dc.contributor.author | David, Sunil A. | - |
| dc.date.accessioned | 2025-10-23T07:27:41Z | - |
| dc.date.available | 2025-10-23T07:27:41Z | - |
| dc.date.issued | 2016 | - |
| dc.identifier.uri | http://localhost:8080/xmlui/handle/123456789/3418 | - |
| dc.description | NITW | en_US |
| dc.description.abstract | Human tolllike receptor (hTLR)8 is expressed in myeloid dendritic cells, monocytes, and monocytederived dendritic cells. Engagement by TLR8 agonists evokes a distinct cytokine profile which favors the development of type 1 helper T cells. Focused exploration of structureactivity relationships in the imidazoquinolines has led to the identification of several novel human TLR8specific agonists. The synthetic procedures for bestinclass analogues encompassing four chemotypes are described. | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | Syntheses of Human TLR8Specific SmallMolecule Agonists Springer | en_US |
| dc.title | Syntheses of Human TLR8Specific SmallMolecule Agonists | en_US |
| dc.type | Article | en_US |
| Appears in Collections: | Chemistry | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Book_Syntheses of Human TLR8-Specific Small-Molecule Agonists - Springer.pdf | 250.1 kB | Adobe PDF | View/Open |
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