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dc.contributor.authorAnugu, Naveenkumar-
dc.contributor.authorThunga, Sanjeeva-
dc.contributor.authorGolla, Sivaparwathi-
dc.contributor.authorKokatlaa, Hari Prasad-
dc.date.accessioned2025-10-23T05:41:58Z-
dc.date.available2025-10-23T05:41:58Z-
dc.date.issued2021-
dc.identifier.citationdoi.org/10.1002/adsc.202100883en_US
dc.identifier.urihttp://localhost:8080/xmlui/handle/123456789/3408-
dc.descriptionNITWen_US
dc.description.abstractA molecular iodine catalyzed regioselective insertion of isocyanide into C2-H of quinoline N-oxides has been developed. The reaction proceeds through the nucleophilic addition of isocyanide on quinoline Noxides followed by rearrangement in presence of iodine. This metal-free reaction affords rapid access to quinoline 2-formamides with exceptional functional group tolerance, broad substrate scope and 100% atomeconomy. A library of 33 N-(2-quinolinyl)formamides are synthesized, which may find applications in pharmaceuticals and synthetic chemistry.en_US
dc.language.isoenen_US
dc.publisherAdvansed Synthesis & Catalysisen_US
dc.subjectFormamidationen_US
dc.subjectIodineen_US
dc.subjectIsocyanidesen_US
dc.subjectN-oxidesen_US
dc.subjectN-(2- quinolinyl)formamidesen_US
dc.titleIodine Catalyzed C2-H Formamidation of Quinoline N-Oxides using Isocyanides: A Metal-Free Approachen_US
dc.typeArticleen_US
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