Please use this identifier to cite or link to this item: http://localhost:8080/xmlui/handle/123456789/3165
Title: A Facile One-Pot Expeditious Synthesis of Thiazolyl-pyrazolones
Authors: Venkata, C.S.R.
Rao, V.R.
Keywords: : Knoevenagel reaction
One pot reaction
Issue Date: 2011
Publisher: Phosphorus, Sulfur, and Silicon and the Related Elements
Abstract: A novel, one-pot, multicomponent synthesis of 4-arylidene-3-methyl-1-(4-arylthiazol-2-yl)-1H-pyrazol-5(4H)-ones is described using phenacyl bromides, thiosemicarbazide, ethylacetoacetate, and aryl aldehydes. This synthesis involves simultaneous formation of two heterocycles like thiazole and pyrazolone along with condensation of active methylene group by aldehydes via Knoevenagel reaction. The methodology is mild, efficient, and high yielding.
Description: NITW
URI: http://localhost:8080/xmlui/handle/123456789/3165
Appears in Collections:Chemistry

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