Please use this identifier to cite or link to this item: http://localhost:8080/xmlui/handle/123456789/3044
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dc.contributor.authorSanthosh, P.-
dc.contributor.authorChunduru, V.S.R-
dc.contributor.authorRajeswar Rao, V.-
dc.date.accessioned2025-01-31T11:03:23Z-
dc.date.available2025-01-31T11:03:23Z-
dc.date.issued2011-
dc.identifier.urihttp://localhost:8080/xmlui/handle/123456789/3044-
dc.descriptionNITWen_US
dc.description.abstractA regioselective enzyme-catalyzed system is selected for the synthesis of 1,3,5-trisubstituted pyrazole derivatives by adding phenyl hydrazines, nitroolefins, and benzaldehydes. The reaction is performed in a one-pot vessel with a yield ranging from 49 to 90%. TLL@MMI, immobilized Thermomyces lanuginosus lipase (TLL) on a multivariate of MOF-5/IRMOF-3 (MMI), showed good performance for the catalysis of this reaction. The prepared biocatalyst was characterized by FTIR, XRD, SEM, and EDX. The thermal and solvent stability of TLL@MMI was investigated in MeOH and EtOH after 24 h incubation. In the presence of 100% concentrations of EtOH, TLL@MMI has 80% activityen_US
dc.language.isoenen_US
dc.publisherKhimiya Geterotsiklicheskikh Soedineniien_US
dc.subjectCatalystsen_US
dc.subjectEthanolen_US
dc.titleOne-pot synthesis of trisubstituted pyrazoles via multicomponent approachen_US
dc.typeArticleen_US
Appears in Collections:Chemistry



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