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dc.contributor.authorRamagiri, Raj Kumar-
dc.contributor.authorVedula, Rajeswar Rao-
dc.contributor.authorThupurani, Murali Krishna-
dc.date.accessioned2024-12-30T10:02:13Z-
dc.date.available2024-12-30T10:02:13Z-
dc.date.issued2015-
dc.identifier.citation10.1080/10426507.2014.990016en_US
dc.identifier.urihttp://localhost:8080/xmlui/handle/123456789/2232-
dc.descriptionNITWen_US
dc.description.abstractA multi-component synthesis of 3-(2-amino-4-thiazolyl)coumarins has been re-ported from 3-(2-bromoacetyl)-2H-chromen-2-ones primary amines and using commerciallyavailable trimethylsilyl isothiocyanate. The structures of newly synthesized compounds werecharacterized by their analytical and spectral data. All the title compounds were screenedfor antioxidant and anti-inflammatory activity. Among the screened compounds, 4b exhibitedhighest free radical scavenging activity and also 4b was found to be effective in inhibiting theprotein denaturation at all tested concentrations.en_US
dc.language.isoenen_US
dc.publisherPhosphorus, Sulfur and Silicon and the Related Elementsen_US
dc.subjectCoumarinen_US
dc.subjectMulti-component reactionen_US
dc.titleA FACILE ONE-STEP MULTI-COMPONENT APPROACHTOWARD THE SYNTHESIS OF3-(2-AMINO-4-THIAZOLYL)COUMARINS BY USINGTRIMETHYLSILYL ISOTHIOCYANATE AND THEIRANTIOXIDANT AND ANTI-INFLAMMATORY ACTIVITYen_US
dc.typeArticleen_US
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