An efficient stereo selective synthesis of benzyl, (benzimidazol-2-yl)methyl and (6H-imidazo[4,5-e][2,1,3]benzothiadiazol-7-yl)methyl styryl sulfones

Abstract

A facile and an efficient one-pot synthesis of (E)-styryl sulfones is described by condensation of 2-(chloromethyl)benzimidazoles or 7-(chloromethyl)-6H-imidazo[4,5-e][2,1,3]benzothiadiazole or benzyl bromides with sodium (E)-styryl sulfinates in DMF gave corresponding styryl sulfones. They have been prepared in good yields, in the absence of any catalyst.