SYNTHESIS  OF SOME NEW  3-(2-OXO-2H-CHROMEN-3-YL)-5H-[ 1,3] THIAZOLO [3,2-a]  ΡYRIMIDINE-5-ONES

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DC Field	Value	Language
dc.contributor.author	Reddy, V.R.	-
dc.contributor.author	Rao, V.R.	-
dc.date.accessioned	2024-11-21T05:06:53Z	-
dc.date.available	2024-11-21T05:06:53Z	-
dc.date.issued	2005	-
dc.identifier.citation	10.1515/HC.2005.11.3-4.299	en_US
dc.identifier.uri	http://localhost:8080/xmlui/handle/123456789/1588	-
dc.description	NITW	en_US
dc.description.abstract	Condensation of 3-(2-amino-4-thiazolyl)coumarins (I) with a-acetyl-y-butyrolactone in a mixture of polyphosphoric acid and POCI3 affords 6-(2-chloromethyl)-7-methyl-3-(2-oxo-2H-chromen-3-yl)-5H-[l,3]-thiazolo[3,2-a] pyrimidine-5-one (Ila-f), while condensation of I with ß-ketoesters gives 7-methyl-3-(2-oxo-2H-chromen-3-yl)-5H-[l,3]thiazolo [3,2-a]pyrimidine-5-ones (IIIa-g). Reaction between I and diethyl methoxy methylene malonate under solvent free c onditions gives 3 -(2-oxo-2H-chromen-3-yl)-5H-[l,3]thiazolo[3,2-a]pyrimidine-5-one-6-carboxylic acid ethyl ester (IV). The structures of newly synthesized compounds have been established by elemental analysis and spectral data	en_US
dc.language.iso	en	en_US
dc.publisher	Heterocyclic Communications	en_US
dc.subject	3-(2-amino-4-thiazolyl)	en_US
dc.subject	ΡYRIMIDINE-5-ONES	en_US
dc.title	SYNTHESIS OF SOME NEW 3-(2-OXO-2H-CHROMEN-3-YL)-5H-[ 1,3] THIAZOLO [3,2-a] ΡYRIMIDINE-5-ONES	en_US
dc.type	Article	en_US
Appears in Collections:	Chemistry

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