SYNTHESIS OF 3-[2-(SUBSTITUTED SULFONYL)-1H-IMIDAZOL-YL] CHROMEN-2-ONE DERIVATIVES

Abstract

Reaction of 3-(2-Mercapto-lH-imidazol-4-yl)chromen-2-one (1) with various alkyl/aryl/phenacyl halides in a mixture of anhydrous ethanol and dimethyl formamide gave the corresponding 3-(2-substituted sulfanyl-lH-imidazol-4- yl)chromen-2-ones (2).These on further reaction with hydrogen peroxide in acetic acid resulted in the formation of corresponding sulfones(3) in good yields. the structure of the synthesized compounds were established from evidences like IR,NMR and mass spectral data