Antifertility agents—synthesis and activity

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DC Field	Value	Language
dc.contributor.author	Rajitha, B.	-
dc.contributor.author	Geetanjali, Y.	-
dc.contributor.author	Rao, M.K.	-
dc.contributor.author	Somayajulu, V.V.	-
dc.contributor.author	Atal, C.K.	-
dc.date.accessioned	2024-11-04T06:05:52Z	-
dc.date.available	2024-11-04T06:05:52Z	-
dc.date.issued	1981	-
dc.identifier.citation	10.1007/BF02879402	en_US
dc.identifier.uri	http://localhost:8080/xmlui/handle/123456789/1352	-
dc.description	NITW	en_US
dc.description.abstract	Basic ethers, 2-phenyl-3-(p-β-dialkylaminoalkoxy)-phenyl 7(H) oxo furanocoumarin(VIa) and 9-methyl analog 2-phenyl-3-(p-β-dialkylaminoalkoxy)-phenyl-9-methyl 7(H) oxo furanocoumarin (VIb) have been synthesised by condensing 2-phenyl-3-p-hydroxyphenyl 7(H) oxo furanocoumarin (Va) and its 9-methyl analog (Vb) with appropriate β-tertiary aminoalkyl halide in acetone-potassium carbonate. Va and Vb were obtained by demethylating the methyl ethers IVa and IVb respectively with pyridine hydrochloride. IVa and IVb themselves were formed from the alkali-induced cyclisation of the ketones IIIa and IIIb. Among the compounds tested for antifertility activity, the basic ethers 12, 14, and 18* were found to have marked anti-implantation properties.	en_US
dc.language.iso	en	en_US
dc.publisher	Proceedings of the Indian Academy of Sciences - Chemical Sciences	en_US
dc.subject	Antifertility agents	en_US
dc.subject	synthesis	en_US
dc.title	Antifertility agents—synthesis and activity	en_US
dc.type	Article	en_US
Appears in Collections:	Chemistry

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